A pilot study conducted at the Medical University of South Carolina (MUSC) suggests that a new approach using transcranial magnetic stimulation (TMS) may hold promise in treating adults with autism and depression. The study aimed to explore the effectiveness of TMS in reducing depressive symptoms in this population. TMS involves using a magnet placed on the scalp to generate electromagnetic pulses that activate neurons near the magnet.
Depression is commonly seen in adults with autism, with rates ranging from 26% to 50%. However, standard antidepressant medications are often less effective and well-tolerated in individuals with autism, and may even worsen their autism symptoms. Furthermore, there are currently no FDA-approved treatments for the core symptoms of autism, emphasizing the need for new therapeutic options.
In the pilot study, daily TMS treatments targeting the brain region associated with depression resulted in a reduction of depressive symptoms in 70% of the participants. While there were no changes in self-reported autism symptoms, there were decreases in repetitive behaviors, hyperactivity, and irritability. Overall, TMS treatments were well-tolerated, with only a few participants experiencing minor side effects such as fatigue, headache, and scalp discomfort.
Despite these promising results, it is important to note that the study had limitations, such as a small number of participants and the absence of randomized, double-blind trials to confirm treatment effectiveness. Therefore, larger studies are needed to determine the effectiveness of TMS in treating adults with autism and depression. Additionally, further research is required to investigate the role of TMS in treating autism symptoms.
The Medical University of South Carolina (MUSC) is the oldest medical school in the South and is known for its focus on education, research, and patient care. MUSC Health, the clinical health system of MUSC, operates eight hospitals and has been named the No. 1 hospital in South Carolina for five consecutive years by U.S. News & World Report. MUSC and its affiliates have a combined annual budget of $3.2 billion and are dedicated to advancing healthcare through innovation and collaboration.
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